UK NPIS 0344 892 0111
Ireland NPIC (01) 809 2566
A service commissioned by
Public Health England (PHE)
on behalf of the UK Health Departments
About the NPIS - TOXBASE
Updated 4/2018


The clinical toxicology database of the National Poisons Information Service


Since 1998 it has been Department of Health policy that the first point of contact for poisons information for health professionals in the UK should be TOXBASE online. This database contains information on approximately 17,000 products, together with generic advice on the management of poisoning. A leaflet can be found here.

TOXBASE online is available free of charge to registered NHS and affiliated users - accounts are issued per unit or department on completion of a registration form

TOXBASE online is also available by paid subscription - click here for further details.

The TOXBASE app (for iOS and Android) is also available to individual users - click here for details.

By using TOXBASE, clinical staff can obtain key clinical information rapidly, including advice on potentially hazardous doses and appropriate management. A printable fact-sheet is available as a permanent record of the advice provided for that patient. The NPIS advises that it is important not to use a previously printed fact-sheet for newly presenting patients. Instead, staff should re-access TOXBASE to obtain the very latest advice, as updates on TOXBASE are performed virtually every day and old fact-sheets rapidly become out of date. The print-outs should not be handed to patients as information sheets.

TOXBASE can be accessed from any computing device using a frames-enabled, JAVA-compliant browser (such as Internet Explorer 7 or above, Chrome, Firefox or Opera).

Comments on the content and advice provided in TOXBASE are always welcome. Each entry is written by the NPIS, approved by all NPIS directors and regularly reviewed. Registered users who wish to discuss how to improve their use of the database are encouraged to contact the NPIS as advice on training can be provided.

The NPIS 24-hour telephone helpline (in the UK 0344 892 0111 and Ireland NPIC (01) 809 2566) is always available for discussion of more complex cases. When appropriate, senior medical staff can discuss their cases directly with an NPIS consultant clinical toxicologist.

Click here for the Terms and Conditions for TOXBASE users.